English
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https://doi.org/10.24843/essential.v22i2.121990
Abstrak
Background: PONV is a common occurrence of postoperative nausea and vomiting, and is an uncomfortable and unpleasant event for patients because it can prolong hospitalization time and increase expenditure. Objective: The aim of this research is to find out the number of PONV incidents at RSUP Prof dr. I.G.N.G The direction and distribution or characteristics of PONV incidence are based on several factors such as; gender, age, smoking habits, type of surgery, type of anesthesia, duration of surgery, and history of chemotherapy. Method: Cross sectional descriptive research with a sample size of 84, applying bivariate analysis to see the percentage chance of PONV independent factors on the incidence of PONV. Results: There were PONV incidents in 26 patients out of 84 patients with a percentage of 31%, with the distribution of PONV incidents based on independent factors with percentages namely; Female (36%), Age 46 – 65 years (35.6%), non-smoker (36.2%), type of surgery with PONV potential (37%), general anesthesia (35.2%), duration of operation >2 hours (50%), and history of chemotherapy (40%) Conclusion: Based on this study, the most common independent predictor of PONV was surgery duration >2 hours (p=0.002). There is insufficient evidence regarding a number of factors, a history of chemotherapy, in the occurrence of PONV.
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Referensi
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3. Chatterjee et all. Figure 1 | Current Concepts in the Management of Postoperative Nausea and Vomiting [Internet]. web page . 2011 [cited 2022 May 11]. Available from: https://www.hindawi.com/journals/arp/2011/748031/fig1/
4. Charles Vacanti SS, PS and RU. Managementof postoperative nausea and vomiting. Essential Clinical Anesthesia [Internet]. 2011 Jan 1 [cited 2022 May 11];326–9. Available from: https://www.cambridge.org/core/books/essential-clinical-anesthesia/managementof-postoperative-nausea-and-vomiting/1F6E73C1FA57F621975076E4ED9CE338
5. Chatterjee S, Rudra A, Sengupta S. Current concepts in the management of postoperative nausea and vomiting. Anesthesiol Res Pract [Internet]. 2011 [cited 2022 May 21];2011. Available from: https://pubmed.ncbi.nlm.nih.gov/22110499/
6. Jin Z, Gan TJ, Bergese SD. Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies. Ther Clin Risk Manag [Internet]. 2020 Dec 31 [cited 2022 May 28];16:1305–17. Available from: https://www.dovepress.com/prevention-and-treatment-of-postoperative-nausea-and-vomiting-ponv-a-r-peer-reviewed-fulltext-article-TCRM
7. Windri TM, Kinasih A, Pratiwi T, Sanubari E, Universitas ), Wacana KS. Angkit Kinasih 2) , Thresia Pratiwi Elingsetyo Sanubari 3) 1444 JMP Online. Tabita Ma Windri. 2019;1(11):1444–51.
8. Doubravska © L, Dostalova K, Fritscherova S, Zapletalova J, Adamus M. INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENTS AT A UNIVERSITY HOSPITAL. WHERE ARE WE TODAY? 2010;154(1):69–76.
9. Elsa Anggrahini. PERBEDAAN PEROKOK AKTIF DAN PEROKOK PASIF TERHADAP KEJADIAN POST OPERATIVE NAUSEA AND VOMITING PADA PASIEN GENERAL ANESTESI DI RSUD SLEMAN. 2017;7–8.
10. Whalen F, Sprung J, Burkle CM, Schroeder DR, Warner DO. Recent smoking behavior and postoperative nausea and vomiting. Anesth Analg [Internet]. 2006;103(1):70–5, table of contents. Available from: http://dx.doi.org/10.1213/01.ane.0000221435.14002.4c
11. Eberhart LHJ, Högel J, Seeling W, Staack AM, Geldner G, Georgieff M. Evaluation of three risk scores to predict postoperative nausea and vomiting. Acta Anaesthesiol Scand [Internet]. 2000 Apr 1 [cited 2022 May 26];44(4):480–8. Available from: https://onlinelibrary.wiley.com/doi/full/10.1034/j.1399-6576.2000.440422.x
12. Apfel CC, Apfel CC, Heidrich FM, Heidrich FM, Jukar-Rao S, Jukar-Rao S, et al. Evidence-based analysis of risk factors for postoperative nausea and vomiting. BJA: British Journal of Anaesthesia [Internet]. 2012; Available from: https://pubmed.ncbi.nlm.nih.gov/23035051
13. Chatterjee S, Chatterjee S, Chatterjee S, Rudra A, Rudra A, Sengupta S, et al. Current Concepts in the Management of Postoperative Nausea and Vomiting. Anesthesiol Res Pract [Internet]. 2011; Available from: https://pubmed.ncbi.nlm.nih.gov/22110499
14. Ahmed AB, Hobbs GJ, Curran JP. Randomized, placebo‐controlled trial of combination antiemetic prophylaxis for day‐case gynaecological laparoscopic surgery†. BJA: British Journal of Anaesthesia [Internet]. 2000 Oct 1 [cited 2022 May 26];85(5):678–82. Available from: https://academic.oup.com/bja/article/85/5/678/273903
15. East J, Mitchell D. Article in The West Indian medical journal. 2009 [cited 2022 May 26]; Available from: https://www.researchgate.net/publication/51594920
16. Tramèr MR. Strategies for postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol [Internet]. 2004 Dec [cited 2022 May 30];18(4):693–701. Available from: https://pubmed.ncbi.nlm.nih.gov/15460553/
17. Aapro M. Granisetron: an update on its clinical use in the management of nausea and vomiting. Oncologist [Internet]. 2004 Nov 1 [cited 2022 May 30];9(6):673–86. Available from: https://pubmed.ncbi.nlm.nih.gov/15561811/
18. Apfel CC, Stoecklein K, Lipfert P. PONV: a problem of inhalational anaesthesia? Best Pract Res Clin Anaesthesiol [Internet]. 2005 [cited 2022 May 30];19(3):485–500. Available from: https://pubmed.ncbi.nlm.nih.gov/16013696/
19. Collins AS. Postoperative nausea and vomiting in adults: implications for critical care. Crit Care Nurse [Internet]. 2011 Dec 1 [cited 2022 May 26];31(6):36–45. Available from: https://pubmed.ncbi.nlm.nih.gov/22135330/
20. Genç A, Can G, Aydiner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer [Internet]. 2013 Jan [cited 2022 May 30];21(1):253–61. Available from: https://pubmed.ncbi.nlm.nih.gov/22678407/
21. Desen W. Buku ajar onkologi klinis [Internet]. Balai Penerbit Fakultas Kedokteran Universitas Indonesia . 2013 [cited 2022 May 30]. Available from: https://lib.ui.ac.id/detail?id=20417330&lokasi=lokal
22. National Cancer Institute. Cancer Drugs - NCI [Internet]. 2022 [cited 2022 May 30]. Available from: https://www.cancer.gov/about-cancer/treatment/drugs
23. Ignatavicius MLWDD. Medical-Surgical Nursing: Concepts for Interprofessional Collaborative Care [Internet]. Philadelphia: W.B. Saunders Company. 2017 [cited 2022 May 30]. Available from: https://bunker2.zlibcdn.com/dtoken/5f9bba84a33bb68aebad50a88ef4a421/Medical-Surgical%20Nursing%20Concepts%20for%20Interprofessional%20Collaborative%20Care%2C%20Single%20Volume%20%28%20etc.%29%20%28z-lib.org%29.pdf
24. Chan HK, Ismail S. Side effects of chemotherapy among cancer patients in a Malaysian General Hospital: experiences, perceptions and informational needs from clinical pharmacists. Asian Pac J Cancer Prev [Internet]. 2014 [cited 2022 May 30];15(13):5305–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25040993/
25. Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med [Internet]. 2008 Jun 5 [cited 2022 May 30];358(23):2482–94. Available from: https://pubmed.ncbi.nlm.nih.gov/18525044/
26. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
27. Smith HS SESB. Postoperative nausea and vomiting. Ann Palliat Med [Internet]. 2012 Oct 1 [cited 2022 May 31];1(2):625–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25841469/
28. Watcha MF, White PF. Postoperative nausea and vomiting. Anesthesiology [Internet]. 1992;77(1):162–84. Available from: http://dx.doi.org/10.1097/00000542-199207000-00023
29. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting. Anesthesiology [Internet]. 1999;91(3):693–693. Available from: http://dx.doi.org/10.1097/00000542-199909000-00022
30. Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg [Internet]. 2020;131(2):411–48. Available from: http://dx.doi.org/10.1213/ANE.0000000000004833
31. Eberhart LHJ, Morin AM, Guber D, Kretz FJ, Schäuffelen A, Treiber H, et al. Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients. Br J Anaesth [Internet]. 2004;93(3):386–92. Available from: http://dx.doi.org/10.1093/bja/aeh221
32. Yatabe T, Tamura T, Yamashita K, Yokoyama M. Influence of dexmedetomidine on cognitive function in volunteers. J Clin Anesth [Internet]. 2016;33:92–6. Available from: http://dx.doi.org/10.1016/j.jclinane.2016.03.017
33. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
34. Apfel CC, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med [Internet]. 2004;350(24):2441–51. Available from: http://dx.doi.org/10.1056/NEJMoa032196
35. Eberhart LHJ, Morin AM. Risk scores for predicting postoperative nausea and vomiting are clinically useful tools and should be used in every patient: con--’life is really simple, but we insist on making it complicated’. Eur J Anaesthesiol [Internet]. 2011;28(3):155–9. Available from: http://dx.doi.org/10.1097/EJA.0b013e3283427f4f
2. Shiraishi-Zapata CJ, Arellano-Adrianzén SJ, Rodríguez-Velarde GJ, Shiraishi-Zapata CJ, Arellano-Adrianzén SJ, Rodríguez-Velarde GJ. Cumulative incidence and risks factors for postoperative nausea and vomiting in adult patients undergoing cholecystectomy under balanced general anesthesia: a prospective cohort study. Colombian Journal of Anestesiology [Internet]. 2020 Jan 1 [cited 2022 Apr 2];48(1):3–11. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-33472020000100003&lng=en&nrm=iso&tlng=en
3. Chatterjee et all. Figure 1 | Current Concepts in the Management of Postoperative Nausea and Vomiting [Internet]. web page . 2011 [cited 2022 May 11]. Available from: https://www.hindawi.com/journals/arp/2011/748031/fig1/
4. Charles Vacanti SS, PS and RU. Managementof postoperative nausea and vomiting. Essential Clinical Anesthesia [Internet]. 2011 Jan 1 [cited 2022 May 11];326–9. Available from: https://www.cambridge.org/core/books/essential-clinical-anesthesia/managementof-postoperative-nausea-and-vomiting/1F6E73C1FA57F621975076E4ED9CE338
5. Chatterjee S, Rudra A, Sengupta S. Current concepts in the management of postoperative nausea and vomiting. Anesthesiol Res Pract [Internet]. 2011 [cited 2022 May 21];2011. Available from: https://pubmed.ncbi.nlm.nih.gov/22110499/
6. Jin Z, Gan TJ, Bergese SD. Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies. Ther Clin Risk Manag [Internet]. 2020 Dec 31 [cited 2022 May 28];16:1305–17. Available from: https://www.dovepress.com/prevention-and-treatment-of-postoperative-nausea-and-vomiting-ponv-a-r-peer-reviewed-fulltext-article-TCRM
7. Windri TM, Kinasih A, Pratiwi T, Sanubari E, Universitas ), Wacana KS. Angkit Kinasih 2) , Thresia Pratiwi Elingsetyo Sanubari 3) 1444 JMP Online. Tabita Ma Windri. 2019;1(11):1444–51.
8. Doubravska © L, Dostalova K, Fritscherova S, Zapletalova J, Adamus M. INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENTS AT A UNIVERSITY HOSPITAL. WHERE ARE WE TODAY? 2010;154(1):69–76.
9. Elsa Anggrahini. PERBEDAAN PEROKOK AKTIF DAN PEROKOK PASIF TERHADAP KEJADIAN POST OPERATIVE NAUSEA AND VOMITING PADA PASIEN GENERAL ANESTESI DI RSUD SLEMAN. 2017;7–8.
10. Whalen F, Sprung J, Burkle CM, Schroeder DR, Warner DO. Recent smoking behavior and postoperative nausea and vomiting. Anesth Analg [Internet]. 2006;103(1):70–5, table of contents. Available from: http://dx.doi.org/10.1213/01.ane.0000221435.14002.4c
11. Eberhart LHJ, Högel J, Seeling W, Staack AM, Geldner G, Georgieff M. Evaluation of three risk scores to predict postoperative nausea and vomiting. Acta Anaesthesiol Scand [Internet]. 2000 Apr 1 [cited 2022 May 26];44(4):480–8. Available from: https://onlinelibrary.wiley.com/doi/full/10.1034/j.1399-6576.2000.440422.x
12. Apfel CC, Apfel CC, Heidrich FM, Heidrich FM, Jukar-Rao S, Jukar-Rao S, et al. Evidence-based analysis of risk factors for postoperative nausea and vomiting. BJA: British Journal of Anaesthesia [Internet]. 2012; Available from: https://pubmed.ncbi.nlm.nih.gov/23035051
13. Chatterjee S, Chatterjee S, Chatterjee S, Rudra A, Rudra A, Sengupta S, et al. Current Concepts in the Management of Postoperative Nausea and Vomiting. Anesthesiol Res Pract [Internet]. 2011; Available from: https://pubmed.ncbi.nlm.nih.gov/22110499
14. Ahmed AB, Hobbs GJ, Curran JP. Randomized, placebo‐controlled trial of combination antiemetic prophylaxis for day‐case gynaecological laparoscopic surgery†. BJA: British Journal of Anaesthesia [Internet]. 2000 Oct 1 [cited 2022 May 26];85(5):678–82. Available from: https://academic.oup.com/bja/article/85/5/678/273903
15. East J, Mitchell D. Article in The West Indian medical journal. 2009 [cited 2022 May 26]; Available from: https://www.researchgate.net/publication/51594920
16. Tramèr MR. Strategies for postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol [Internet]. 2004 Dec [cited 2022 May 30];18(4):693–701. Available from: https://pubmed.ncbi.nlm.nih.gov/15460553/
17. Aapro M. Granisetron: an update on its clinical use in the management of nausea and vomiting. Oncologist [Internet]. 2004 Nov 1 [cited 2022 May 30];9(6):673–86. Available from: https://pubmed.ncbi.nlm.nih.gov/15561811/
18. Apfel CC, Stoecklein K, Lipfert P. PONV: a problem of inhalational anaesthesia? Best Pract Res Clin Anaesthesiol [Internet]. 2005 [cited 2022 May 30];19(3):485–500. Available from: https://pubmed.ncbi.nlm.nih.gov/16013696/
19. Collins AS. Postoperative nausea and vomiting in adults: implications for critical care. Crit Care Nurse [Internet]. 2011 Dec 1 [cited 2022 May 26];31(6):36–45. Available from: https://pubmed.ncbi.nlm.nih.gov/22135330/
20. Genç A, Can G, Aydiner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer [Internet]. 2013 Jan [cited 2022 May 30];21(1):253–61. Available from: https://pubmed.ncbi.nlm.nih.gov/22678407/
21. Desen W. Buku ajar onkologi klinis [Internet]. Balai Penerbit Fakultas Kedokteran Universitas Indonesia . 2013 [cited 2022 May 30]. Available from: https://lib.ui.ac.id/detail?id=20417330&lokasi=lokal
22. National Cancer Institute. Cancer Drugs - NCI [Internet]. 2022 [cited 2022 May 30]. Available from: https://www.cancer.gov/about-cancer/treatment/drugs
23. Ignatavicius MLWDD. Medical-Surgical Nursing: Concepts for Interprofessional Collaborative Care [Internet]. Philadelphia: W.B. Saunders Company. 2017 [cited 2022 May 30]. Available from: https://bunker2.zlibcdn.com/dtoken/5f9bba84a33bb68aebad50a88ef4a421/Medical-Surgical%20Nursing%20Concepts%20for%20Interprofessional%20Collaborative%20Care%2C%20Single%20Volume%20%28%20etc.%29%20%28z-lib.org%29.pdf
24. Chan HK, Ismail S. Side effects of chemotherapy among cancer patients in a Malaysian General Hospital: experiences, perceptions and informational needs from clinical pharmacists. Asian Pac J Cancer Prev [Internet]. 2014 [cited 2022 May 30];15(13):5305–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25040993/
25. Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med [Internet]. 2008 Jun 5 [cited 2022 May 30];358(23):2482–94. Available from: https://pubmed.ncbi.nlm.nih.gov/18525044/
26. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
27. Smith HS SESB. Postoperative nausea and vomiting. Ann Palliat Med [Internet]. 2012 Oct 1 [cited 2022 May 31];1(2):625–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25841469/
28. Watcha MF, White PF. Postoperative nausea and vomiting. Anesthesiology [Internet]. 1992;77(1):162–84. Available from: http://dx.doi.org/10.1097/00000542-199207000-00023
29. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting. Anesthesiology [Internet]. 1999;91(3):693–693. Available from: http://dx.doi.org/10.1097/00000542-199909000-00022
30. Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg [Internet]. 2020;131(2):411–48. Available from: http://dx.doi.org/10.1213/ANE.0000000000004833
31. Eberhart LHJ, Morin AM, Guber D, Kretz FJ, Schäuffelen A, Treiber H, et al. Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients. Br J Anaesth [Internet]. 2004;93(3):386–92. Available from: http://dx.doi.org/10.1093/bja/aeh221
32. Yatabe T, Tamura T, Yamashita K, Yokoyama M. Influence of dexmedetomidine on cognitive function in volunteers. J Clin Anesth [Internet]. 2016;33:92–6. Available from: http://dx.doi.org/10.1016/j.jclinane.2016.03.017
33. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
34. Apfel CC, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med [Internet]. 2004;350(24):2441–51. Available from: http://dx.doi.org/10.1056/NEJMoa032196
35. Eberhart LHJ, Morin AM. Risk scores for predicting postoperative nausea and vomiting are clinically useful tools and should be used in every patient: con--’life is really simple, but we insist on making it complicated’. Eur J Anaesthesiol [Internet]. 2011;28(3):155–9. Available from: http://dx.doi.org/10.1097/EJA.0b013e3283427f4f
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2025-04-06
##submission.howToCite##
BAGASKARA, Joshua Andito et al.
English.
Essence of Scientific Medical Journal, [S.l.], v. 22, n. 2, p. 99-109, apr. 2025.
ISSN 2655-6472.
Tersedia pada: <http://103.29.196.112/index.php/essential/article/view/121990>. Tanggal Akses: 04 mar. 2026
doi: https://doi.org/10.24843/essential.v22i2.121990.
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